Successful Treatment of Prolonged, Severe Coronavirus Disease 2019 Lower Respiratory Tract Disease in a B cell Acute Lymphoblastic Leukemia Patient With an Extended Course of Remdesivir and Nirmatrelvir/Ritonavir.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 36326680.
- Also identified by DOI 10.1093/cid/ciac868 and PMC identifier 10226728.
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Abstract
A patient with B-cell acute lymphoblastic leukemia (ALL) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had persistent, progressive pneumonia with viremia after 5 months of infection despite monoclonal antibodies, intravenous (IV) remdesivir and prolonged oral steroids. Twenty days of nirmatrelvir/ritonavir and 10 days of IV remdesivir led to full recovery.
Medical subject headings
- COVID-19
- Precursor Cell Lymphoblastic Leukemia-Lymphoma