COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 36332771.
- Also identified by DOI 10.1016/j.ypmed.2022.107326 and PMC identifier 9625845.
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Abstract
We retrieved data on a cohort of medical patients at a regional Israeli hospital. The dependent variable was non-COVID-19 hospital mortality; the independent variables were vaccination status, age, and laboratory data. Serum sodium, age, serum creatinine, and COVID-19 vaccination status were the main independent variables associated with non-COVID-19 mortality. The odds ratio for in-hospital deaths of non-vaccinated patients was 2.01 (1.65-2.44) (unadjusted) and 1.61 (1.29-2.03) after adjustment for the independent variables. This "healthy adherer effect" may confound observational assessments of the clinical efficacy of COVID-19 vaccines.
Medical subject headings
- COVID-19 Vaccines
- COVID-19