Association Between the Development of Subclinical Cardiovascular Disease and Human Immunodeficiency Virus (HIV) Reservoir Markers in People With HIV on Suppressive Antiretroviral Therapy.

Turcotte, Isabelle; El-Far, Mohamed; Sadouni, Manel; Chartrand-Lefebvre, Carl; Filali-Mouhim, Ali; Fromentin, Rémi; Chamberland, Annie; Jenabian, Mohammad-Ali et al. · Clin Infect Dis · 2023

cross_sectional · Level IV

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Abstract

We report that people with human immunodeficiency virus (HIV) diagnosed with coronary artery atherosclerotic plaques display higher levels of HIV DNA compared with those without atherosclerotic plaques. In a multivariable prediction model that included 27 traditional and HIV-related risk factors, measures of HIV DNA were among the most important predictors of atherosclerotic plaque formation.

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