Association of CT Findings With Perineural Invasion in Gallbladder Cancer: Preliminary Assessment.

Marodia, Yashi; Kharel, Jyoti; Saikia, Uma N; Kumar, Rajender; Yadav, Thakur D; Gupta, Vikas; Kaman, Lileshwar; Das, Chandan K et al. · AJR Am J Roentgenol · 2023

retrospective_cohort · Level III

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Abstract

Perineural invasion (PNI) indicates a worse prognosis for patients with gallbladder cancer (GBC). This preliminary retrospective study included 19 patients with GBC who under-went contrast-enhanced CT in the 4 weeks before undergoing surgical resection. GBC showed PNI on pathologic assessment in eight of 19 patients. On CT, wall thickening morphology had sensitivity of 75.0% and specificity of 81.8% for PNI; soft-tissue stranding around the celiac plexus had sensitivity of 62.5% and specificity of 100.0% for PNI.

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