Methotrexate induced pneumonitis - A case report and review of literature.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 36352932.
- Also identified by DOI 10.4103/jfmpc.jfmpc_280_22 and PMC identifier 9638664.
- Licence recorded as CC BY-NC-SA.
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Abstract
Methotrexate (MTX) is the commonly preferred drug in the treatment of various chronic inflammatory conditions. An uncommon, life-threatening, and fatal event associated with methotrexate use is methotrexate-induced pneumonitis (M-pneu). M-pneu does not correlate with the dosage, duration, or method of administration. We present a case of M-pneu in a diagnosed rheumatoid arthritis patient after six years of initiation of MTX. Prompt recognition, withdrawal, and supportive therapy have a positive outcome. If untreated, M-pneu has a proven fatality of 17-30% in published cases.