BIPS-A code base for designing and coding of a Phage ImmunoPrecipitation Oligo Library.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36355866.
- Also identified by DOI 10.1371/journal.pcbi.1010663 and PMC identifier 9681064.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
BIPS (Build Phage ImmunoPrecipitation Sequencing library) is a software that converts a list of proteins into a custom DNA oligonucleotide library for the PhIP-Seq system. The tool creates constant-length oligonucleotides with internal barcodes, while maintaining the original length of the peptide. This allows using large libraries, of hundreds of thousands of oligonucleotides, while saving on the costs of sequencing and maintaining the accuracy of oligonucleotide reads identification. BIPS is available under GNU public license from: https://github.com/kalkairis/BuildPhIPSeqLibrary.
Medical subject headings
- Bacteriophages