Omics goes spatial epigenomics.

Schueder, Florian; Bewersdorf, Joerg · Cell · 2022

review · Level V

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Abstract

Spatial omics techniques generate spatially resolved, comprehensive data about molecules that define the identity and function of cells in tissues. Epigenetic multiplexing approaches such as Multiplexed Error-robust FISH (MERFISH), introduced by Lu et al.<sup>1</sup> in this issue of Cell, now allows researchers to study the epigenomic regulation of gene expression in a tissue-region specific manner.

Medical subject headings