ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 36387725.
- Also identified by DOI 10.4103/jfmpc.jfmpc_1663_21 and PMC identifier 9648224.
- Licence recorded as CC BY-NC-SA.
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Abstract
A 45-year-old female, a new case of acute promyelocytic leukemia (APL), received induction chemotherapy containing all-<i>trans</i> retinoic acid (ATRA) and idarubicin. On the sixth day of therapy, she developed sinus bradycardia and differentiation syndrome (DS). Electrolytes and cardiac imaging were normal. The patient achieved normal sinus rhythm after ATRA was withheld, and DS was treated.