Frailty: A Multidimensional Biopsychosocial Syndrome.

Cohen, Carl I; Benyaminov, Rivka; Rahman, Manumar; Ngu, Dilys; Reinhardt, Michael · Med Clin North Am · 2023

review · Level V

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Abstract

The original conceptual landscape of frailty has evolved into a complex, multidimensional biopsychosocial syndrome. This has broadened the field to now include social and behavioral scientists and clinicians from a wide range of specialties. This article aims to provide an updated overview of this conceptual change by examining the emerging definitions of physical, cognitive, social, and psychological frailty; the tools used for diagnosis and assessment of these domains; the epidemiology of the domains; their pathogenesis, risk factors, and course; frameworks for prevention and treatment; and unresolved issues affecting the field.

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