Prevalence of Parvovirus B19 Viremia Among German Blood Donations and the Relationship to ABO and Rhesus Blood Group Antigens.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 36408632.
- Also identified by DOI 10.1093/infdis/jiac456 and PMC identifier 10175064.
- Licence recorded as CC BY-NC-ND.
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Abstract
Asymptomatic blood donors can transmit human parvovirus B19 (B19V). We assessed the B19V prevalence among a large cohort of blood donations collected in Germany during 2015-2018. In total, 167 123 donations were screened for B19V deoxyribonucleic acid with 22 cases of viremia identified (0.013% positive). Infections peaked at a 4-year interval and the highest number of cases occurred in the summer months. All 22 infections were found in rhesus D-antigen-positive donations, suggesting a protective factor in donors who lack this antigen. These findings contribute to our understanding of risk factors for B19V infection among central European blood and plasma donors.
Medical subject headings
- Blood Donation
- Parvoviridae Infections
- Parvovirus B19, Human
- Viremia
- ABO Blood-Group System
- Rh-Hr Blood-Group System