Immune cell heterogeneity in a mouse model of diabetic kidney disease.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36411016.
- Also identified by DOI 10.1016/j.kint.2022.09.007.
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Abstract
Typical kidney single-cell RNA-sequencing contains relatively few leukocytes, complicating efforts to understand how immune cells impact kidney disease progression. In this issue, Fu et al. use a flow sorting strategy to generate a very large immune cell single-cell RNA-sequencing atlas in a mouse model of diabetic kidney disease. These findings highlight the importance of leukocyte cell subtypes in diabetic kidney disease.
Medical subject headings
- Diabetic Nephropathies
- Diabetes Mellitus