Need for speed: Key driver of host cell migration varies among mycobacteria.

Youngblom, Madison A; Pepperell, Caitlin S · Cell · 2022

editorial · Level V

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Abstract

In this issue of Cell, Saelens et al. describe a new function for mycobacterial Type VII secretion systems: manipulation of host cell migration. They find that a substantial proportion of global TB cases arise from bacteria lacking this function, raising questions about its role in pathoadaptation of Mycobacterium tuberculosis.

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