Active DNA demethylation damages DNA.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36454845.
- Also identified by DOI 10.1126/science.adf3171 and PMC identifier 10686637.
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Abstract
Active DNA demethylation maintains enhancer activity in nonproliferating cells but can damage DNA.
Medical subject headings
- DNA Demethylation
- Enhancer Elements, Genetic
- DNA Breaks, Single-Stranded