Modeling brain disorders using transplanted organoids: Beyond the short circuit.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36459963.
- Also identified by DOI 10.1016/j.stem.2022.11.002.
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Abstract
Human cortical organoids transplanted into the somatosensory cortex of rats integrate into the host neural circuits, receive inputs from host cells, and can produce behavioral responses. In a publication in Nature, Revah et al.<sup>1</sup> highlight the potential of this platform for modeling circuit defects associated with neurodevelopmental disorders.
Medical subject headings
- Brain Diseases
- Neurodevelopmental Disorders