Bioresorbable polylactic acid (PLA) and bioactive glasses (BG) composite: Influence of gold coated of BG powder on mechanical properties and chemical reactivity.

Chaigneau, Louis; Perrot, Aurelien; Brezulier, Damien; Coulon, Jean-Francois; Chevire, Francois; Lebullenger, Ronan · J Mech Behav Biomed Mater · 2023

biomechanical · Level V

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Abstract

Due to the ageing of the population, the synthesis of biomaterials and the optimization of their physico-chemical characteristics are at the heart of many research projects in regenerative medicine. The emergence of 3D printing techniques has rapidly led to the manufacture PLA-BG composite scaffolds using the FFF (Fused Filament Fabrication) technique. However, this composite presents some problems including a lower mechanical strength than the two compounds alone, probably due to the ionic salting-out induced by the BG. This study aims to counter this phenomenon by coating the BG particles with a thin layer of gold. The 3D composite objects will then be characterized mechanically and biologically to ensure that the bioactive character of the composite is preserved.

Medical subject headings