Association between high-sensitivity-CRP and liver elastography and cardiac ischemic diseases in patients with fatty liver.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 36505545.
- Also identified by DOI 10.4103/jfmpc.jfmpc_2223_21 and PMC identifier 9731058.
- Licence recorded as CC BY-NC-SA.
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Abstract
Inflammatory markers are among the possible contributing factors with a proposed role in hepatic and ischemic heart disease. The present study aimed to determine the association between high-sensitivity-C-reactive protein (hs-CRP), liver elastography, and cardiac ischemic diseases in patients with fatty liver. In this cross-sectional comparative study, 103 consecutive patients with fatty liver were enrolled to undergo angiography. They were divided into groups with and without cardiac ischemia. The results demonstrated that the mean hs-CRP was 2.3 and 10.9 mg/L in normal and ischemic angiography groups, respectively (<i>P</i> = 0.001). According to the receiver operating characteristic (ROC) analysis, the predictive role for hs-CRP was 94.5% that had sensitivity and specificity of 95.2% and 90%, respectively, with a cut-off point of 3.1. This study showed that there is an association between the fatty liver, cardiac ischemia, and hs-CRP level.