Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view.

Motschi, Alice R; Schwarzhans, Florian; Desissaire, Sylvia; Steiner, Stefan; Bogunović, Hrvoje; Roberts, Philipp K; Vass, Clemens; Hitzenberger, Christoph K et al. · PLoS One · 2022

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Abstract

We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects including both healthy and diseased eyes. Age and sex related differences in the depolarizing character of the RPE are investigated.

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