Self-assembly of alkyl-perylenebisdiimide-DNA amphiphiles and control of their morphology through cyclodextrin-based host-guest interaction.

Gao, Jinyu; Ma, Jiahui; Deng, Cheng; Yang, Hai; Liu, Simin; Zhao, Zhiyong · Soft Matter · 2023

basic_science · Level V

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Abstract

Amphiphilic alkyl-perylenebisdiimide-DNA hybrids self-assemble into spherical micelles and transform into nanofibers upon the addition of β-cyclodextrins due to host-guest interaction. A competitive guest can induce the nanofibers to reversibly change back to spherical micelles. Both spherical micelles and nanofibers can anchor functional molecules at the corona through DNA hybridization.

Medical subject headings