New use for an old drug: Metformin and atrial fibrillation.

Vinciguerra, Manlio; Olier, Ivan; Ortega-Martorell, Sandra; Lip, Gregory Y H · Cell Rep Med · 2022

basic_science · Level V

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Abstract

Lal and colleagues<sup>1</sup> reported an integrative approach-combining transcriptomics, iPSCs, and epidemiological evidence-to identify and repurpose metformin, a main first-line medication for the treatment of type 2 diabetes, as an effective risk reducer for atrial fibrillation.

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