The use of Vaccinia Immune Globulin in the Treatment of Severe Mpox. Virus Infection in Human Immunodeficiency Virus/AIDS.

Thet, Andrea K; Kelly, Paul J; Kasule, Sabirah N; Shah, Anish K; Chawala, Arpan; Latif, Amber; Chilimuri, Sridhar S; Zeana, Cosmina B · Clin Infect Dis · 2023

case_report · Level V

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Abstract

We report a case of progressive, severe mpox virus (MPXV) infection in a patient with AIDS despite a standard course of tecovirimat. He significantly improved after administration of vaccinia immune globulin intravenous (VIGIV) highlighting its use as an adjunct for severe disease in immunocompromised hosts.

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