The Achilles heel of TNBCs: Ferroptosis heterogeneity.
other · Level V
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- Record sourced from PubMed, PMID 36599296.
- Also identified by DOI 10.1016/j.cmet.2022.11.014.
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Abstract
Resistance to ferroptosis, a form of programmed cell death, is associated with the development of some refractory cancers. In this issue, Yang et al. systematically illustrate the ferroptosis heterogeneity in triple-negative breast cancers (TNBCs) and reveal an innovative immunotherapy combination strategy for the luminal androgen receptor (LAR) subtype of TNBC.
Medical subject headings
- Ferroptosis
- Triple Negative Breast Neoplasms