Ferritin-induced NETs lead to cytokine storm in AOSD.

Onuora, Sarah · Nat Rev Rheumatol · 2023

basic_science · Level V

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Abstract

New research reveals that ferritin has an essential role in neutrophil extracellular trap (NET)-mediated inflammation, and suggests that NETs or the ferritin receptor MSR1 could be targeted for the treatment of adult-onset Still disease.

Medical subject headings