Strength in diversity: Intra-cellular metabolite sharing enhances longevity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36608660.
- Also identified by DOI 10.1016/j.cell.2022.12.012.
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Abstract
Much of our foundational knowledge of cellular biology comes from studies in budding yeast, often described as a simple unicellular eukaryotic model. In this issue of Cell, Correia-Melo et al. describe an unappreciated feature of yeast biology involving intra-cellular metabolite exchange, where cells adapt and respond as part of a community, and go on to show that sharing of resources linked to methionine metabolism enhances longevity of cooperating cells.
Medical subject headings
- Longevity
- Saccharomycetales