Approaching complete genomes, transcriptomes and epi-omes with accurate long-read sequencing.

Kovaka, Sam; Ou, Shujun; Jenike, Katharine M; Schatz, Michael C · Nat Methods · 2023

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Abstract

The year 2022 will be remembered as the turning point for accurate long-read sequencing, which now establishes the gold standard for speed and accuracy at competitive costs. We discuss the key bioinformatics techniques needed to power long reads across application areas and close with our vision for long-read sequencing over the coming years.

Medical subject headings