Mapache: a flexible pipeline to map ancient DNA.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 36637197.
- Also identified by DOI 10.1093/bioinformatics/btad028 and PMC identifier 9901408.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We introduce mapache, a flexible, robust and scalable pipeline to map, quantify and impute ancient and present-day DNA in a reproducible way. Mapache is implemented in the workflow manager Snakemake and is optimized for low-space consumption, allowing to efficiently (re)map large datasets-such as reference panels and multiple extracts and libraries per sample - to one or several genomes. Mapache can easily be customized or combined with other Snakemake tools. Mapache is freely available on GitHub (https://github.com/sneuensc/mapache). An extensive manual is provided at https://github.com/sneuensc/mapache/wiki. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Software
- DNA, Ancient