Is psilocybin an effective antidepressant and what is its Mechanism of action?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 36652915.
- Also identified by DOI 10.1016/j.xcrm.2022.100906 and PMC identifier 9873942.
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Abstract
Goodwin et al.<sup>1</sup> report a single 25 mg dose of psilocybin has an antidepressant effect short-term in medication-resistant depression. Unanswered questions include drug blood level as a guide to dose, psychedelic effects relationship to antidepressant benefit, and potential suicide risk of psilocybin.
Medical subject headings
- Psilocybin
- Hallucinogens