Proteome-based insights for IDH-mutant glioma classification.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36652918.
- Also identified by DOI 10.1016/j.xcrm.2022.100909 and PMC identifier 9873937.
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Abstract
In this issue, Bader et al.<sup>1</sup> characterize the proteomes of diffuse glioma brain tumors by liquid chromatography mass spectrometry and classify isocitrate dehydrogenase (IDH)-mutant gliomas into two subtypes, which differ in oncogenic pathways and aerobic/anaerobic energy metabolism.
Medical subject headings
- Glioma
- Brain Neoplasms