Coordinated cancer chaos.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 36669470.
- Also identified by DOI 10.1016/j.cell.2022.12.015.
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Abstract
Stochastic processes, such as genetic instability and microenvironment evolution, drive tumor heterogeneity, thereby creating the chaotic appearance of tumors in histopathology. In this issue of Cell, Lin et al. reveal that tumors are surprisingly spatially organized from a molecular to tissue scale, indicating that cancers evolve as autonomously patterned systems.
Medical subject headings
- Nonlinear Dynamics
- Neoplasms