SON-light activation of glucose regulation.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 36669471.
- Also identified by DOI 10.1016/j.cell.2022.12.045 and PMC identifier 10246588.
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Abstract
Body temperature maintenance is an important regulator of glucose homeostasis. In this issue of Cell, Meng et al. discover a regulatory axis in which light activation of photoreceptive retinal ganglia stimulates the supraoptic nucleus (SON) to inhibit brown adipose tissue (BAT) thermogenesis and impair glucose homeostasis. This could explain the impact of constant light exposure on metabolism.
Medical subject headings
- Glucose
- Supraoptic Nucleus