Viewing RCC with a DNA Methylation Lens ENHANCES Understanding of ICI Resistance.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 36700785.
- Also identified by DOI 10.1158/1078-0432.CCR-22-3574 and PMC identifier 10073255.
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Abstract
Clear-cell renal cell carcinoma tumors with an enhancer demethylator phenotype (TED) harbor a worse prognosis and derive less clinical benefit from immunotherapy. The TED phenotype may help predict immunotherapy resistance. See related article by Lu et al., p. 1279.
Medical subject headings
- Carcinoma, Renal Cell
- Kidney Neoplasms