Spatial tropism profiling of AAV vectors by ultrasensitive sequential FISH in tissue.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36717693.
- Also identified by DOI 10.1038/s41587-023-01681-3 and PMC identifier 9885914.
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Abstract
Ultrasensitive sequential fluorescence in situ hybridization (USeqFISH) enables multiplexed detection of the expression of endogenous and exogenous genes delivered by adeno-associated virus (AAV) vectors in intact tissue. USeqFISH provides a spatial map of AAV tropism with high throughput and resolution.
Medical subject headings
- Tropism
- Gene Transfer Techniques