Pain Science in Practice (Part 5): <i>Central Sensitization II</i>.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 36722100.
- Also identified by DOI 10.2519/jospt.2023.11571.
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Abstract
<b>SYNOPSIS:</b> <i>Central sensitization is an umbrella-term for facilitated synaptic plasticity. This editorial explains wind-up, classical central sensitization, and long-term potentiation. Wind-up and LTP are generally considered homosynaptic, while classical central sensitization is classified as heterosynaptic. Wind-up is very short lived and unlikely to play a significant role in chronic musculoskeletal pain, however, both LTP and classical central sensitization could potentially be involved in chronic pain. J Orthop Sports Phys Ther 2023;53(2):55-58. doi:10.2519/jospt.2023.11571</i>.
Medical subject headings
- Chronic Pain
- Musculoskeletal Pain