Vertebral Body Osteonecrosis Mimicking Malignant Disease on 18F-FDG PET.
case_report · Level V
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- Record sourced from PubMed, PMID 36723894.
- Also identified by DOI 10.1097/RLU.0000000000004453.
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Abstract
We report a case of vertebral osteonecrosis after chemotherapy in a 24-year-old man with non-Hodgkin lymphoma, with transient avidity on 18F-FDG PET initially misinterpreted as recurrent extranodal disease. The patient demonstrated a partial metabolic response on midtreatment restaging PET; however, posttreatment PET showed an increase in uptake in T4 and T5 vertebrae, interpreted as recurrent vertebral disease. Repeat PET performed 9 days later showed resolution of thoracic vertebral uptake without interval treatment. On follow-up PET study, thoracic vertebrae demonstrated photopenia with sclerosis on CT, concerning for osteonecrosis. MRI features were concordant with this diagnosis.
Medical subject headings
- Fluorodeoxyglucose F18
- Vertebral Body