Langerhans Cell Histiocytosis of Bilateral Parotid and Submandibular Glands: Findings on 18F-FDG PET/CT.

Prakash, Sneha; Shamim, Shamim Ahmed; Bakhshi, Sameer; Pushpam, Deepam; Sharma, Aparna · Clin Nucl Med · 2023

case_report · Level V

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Abstract

Langerhans cell histiocytosis is a disorder of the mononuclear phagocytic system. Virtually any organ can be involved, the bone, skin, lungs, and pituitary gland being the most common. We describe the case of a 30-year-old man who presented with painless neck swelling. 18 F-FDG PET/CT showed bilateral bulky parotid and submandibular glands with increased metabolic activity. Histopathology confirmed the diagnosis of Langerhans cell histiocytosis. To our knowledge, there has been no description of 18 F-FDG PET/CT findings in Langerhans cell histiocytosis of salivary glands in literature. We aim to aid in the diagnosis and management of this rare presentation.

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