Extrastriatal 99m Tc-TRODAT-1 Uptake in the Previous Hemorrhage With Hemosiderin Deposition.

Lee, Tse-Hao; Wang, Yuh-Feng; Peng, Nan-Jing · Clin Nucl Med · 2023

case_report · Level V

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Abstract

We reported a 91-year-old man who was suspected of having parkinsonism, and brain 99m Tc-TRODAT-1 scan revealed an extrastriatal uptake in the left side of brainstem, which was correlated to a previously hemorrhagic lesion with hemosiderin deposition. Macrophage or microglia might accumulate in the previous hemorrhagic lesion to phagocytize hemosiderin. We assumed that the 99m Tc-TRODAT-1 uptake in the hemosiderin deposition might be partially mediated by macrophage expressing dopamine transporter.

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