When IL-17 gets on your nerves.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36736299.
- Also identified by DOI 10.1016/j.cell.2022.12.048 and PMC identifier 10967262.
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Abstract
Microbiota-induced IL-17 production mediates CNS processes and animal behavior. However, its role on the peripheral nervous system (PNS) remains largely unknown. Enamorado et al. demonstrate that commensal-specific Th17 cells are recalled following tissue injury to support local nerve regeneration, a process orchestrated by IL-17 signaling on peripheral neurons.
Medical subject headings
- Central Nervous System
- Interleukin-17