In hypertension, evening vs. morning dosing of antihypertensive drugs did not differ for major CV outcomes at 5.2 y.

Aung, KoKo; Htay, Thwe · Ann Intern Med · 2023

rct · Level II

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Abstract

Mackenzie IS, Rogers A, Poulter NR, et al. <b>Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial.</b> Lancet. 2022;400:1417-25. 36240838.

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