Metabolic individuality: Limitations, challenges, and potential for clinical utility.
editorial · Level V
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- Record sourced from PubMed, PMID 36754017.
- Also identified by DOI 10.1016/j.cmet.2023.01.007.
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Abstract
In Nature Medicine, Surendran and colleagues recently reported the analysis of human plasma metabolomic data for 913 metabolites in ∼20,000 individuals, identifying 2,599 metabolite-genetic variant associations and >400 metabolite signatures comprised of jointly regulated metabolites. This extensive atlas of variant-metabolite relationships reveals novel genomic mechanisms driving metabolic phenotypes.
Medical subject headings
- Metabolomics
- Metabolome