Effect of Patient and Family Centered I-PASS on adverse event rates in hospitalized children with complex chronic conditions.

Abstract

Children with complex chronic conditions (CCCs) are at risk for adverse events (AEs) during hospitalizations. We compared the effect of Patient and Family Centered (PFC)I-PASS on AE rates in children with and without CCCs. Patients were drawn from the PFCI-PASS study, which included 3106 hospitalized children from seven North American pediatric hospitals between December 2014 and January 2017. An effect modification analysis did not show difference in the intervention on children with and without CCCs (RRR 0.81, 95% CI [0.59-1.10]; p = .2). In multivariable analysis, the adjusted incidence rate ratiofor AEs in children with CCCs was 0.5 (95% CI = 0.3-0.9, p = .01) with PFC I-PASS exposure; there was no statistically significant change in AEs for children without CCCs [IRR 0.6 (95% CI = 0.3-1.2; p = .1)].