Reducing decoys focuses fighting microglia.
Where this comes from
- Record sourced from PubMed, PMID 36793992.
- Also identified by DOI 10.1038/s43587-022-00251-7 and PMC identifier 9928165.
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Abstract
Genetic variation linked to lower levels of soluble ST2, a decoy cytokine receptor for IL-33, may protect against Alzheimer's disease in female <i>APOE</i>ε4 carriers by increasing microglial plaque removal. This discovery advances our understanding of the immune system's role in Alzheimer's disease and underscores the importance of sex-specific disease processes.
Medical subject headings
- Alzheimer Disease