Increased 18 F-Fluoroestradiol Uptake of Radiation Pneumonitis in a Patient With Metastatic Breast Cancer.

Pan, Bo; Hao, Zhixin; Zhou, Yidong; Sun, Qiang; Huo, Li · Clin Nucl Med · 2023

case_report · Level V

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Abstract

A 42-year-old woman diagnosed with de-novo stage IV breast cancer underwent 18 F-fluoroestradiol (FES) PET/CT to evaluate the estrogen receptor status of metastatic lesions. The largest pulmonary nodule showed obvious FES uptake, consistent with pulmonary metastases from breast cancer. Interestingly, the images revealed a striking accumulation of FES in ground-glass attenuation in the left lobe of lung, suggestive of radiation pneumonitis.

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