Large-scale genomic analyses reveal alterations and mechanisms underlying clonal evolution and immune evasion in esophageal cancer.
Level V
Where this comes from
- Record sourced from PubMed, PMID 36807265.
- Also identified by DOI 10.1038/s41467-023-36557-2 and PMC identifier 9938131.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Esophageal cancers feature distinct manifestations between and within patients which complicate precision diagnosis, prognosis, and patient care. New genomic and epigenomic research uncovers novel mechanisms underlying both inter- and intra-tumoral heterogeneity in esophageal cancer, with significant biological and translational implications.
Medical subject headings
- Immune Evasion
- Esophageal Neoplasms