Enhancer Coamplification and Hijacking Promote Oncogene Expression in Liposarcoma.

Liu, Tingting; Wang, Juan; Yang, Hongbo; Jin, Qiushi; Wang, Xiaotao; Fu, Yihao; Luan, Yu; Wang, Qixuan et al. · Cancer Res · 2023

basic_science · Level V

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Abstract

Comprehensive profiling of the enhancer landscape and 3D genome structure in liposarcoma identifies extensive enhancer-oncogene coamplification and enhancer hijacking events, deepening the understanding of how oncogenes are regulated in cancer.

Medical subject headings