peaks2utr: a robust Python tool for the annotation of 3' UTRs.
basic_science · Level V
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- Record sourced from PubMed, PMID 36864613.
- Also identified by DOI 10.1093/bioinformatics/btad112 and PMC identifier 10008064.
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Abstract
Annotation of nonmodel organisms is an open problem, especially the detection of untranslated regions (UTRs). Correct annotation of UTRs is crucial in transcriptomic analysis to accurately capture the expression of each gene yet is mostly overlooked in annotation pipelines. Here we present peaks2utr, an easy-to-use Python command line tool that uses the UTR enrichment of single-cell technologies, such as 10× Chromium, to accurately annotate 3' UTRs for a given canonical annotation. peaks2utr is implemented in Python 3 (≥3.8). It is available via PyPI at https://pypi.org/project/peaks2utr and GitHub at https://github.com/haessar/peaks2utr. It is licensed under GNU GPLv3.
Medical subject headings
- Software
- Gene Expression Profiling