AMD recapitulated in a 3D biomimetic: A breakthrough in retina tissue engineering.

Dalvi, Sonal; Chatterjee, Amit; Singh, Ruchira · Cell Stem Cell · 2023

editorial · Level V

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Abstract

Song et al. (Nature Methods, 2022) engineered a 3D model of the human outer blood-retina barrier (oBRB) that recapitulates key features of healthy and age-related macular degeneration (AMD)-affected eyes.<sup>1</sup> We shine a spotlight on this tissue-engineering triumph that has the potential to transform preclinical studies of AMD and other eye diseases.

Medical subject headings