Bat crazy iPSCs.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36868212.
- Also identified by DOI 10.1016/j.cell.2023.01.033.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Accelerating the development of tools for non-model animal research, Dejosez et al. report the generation of induced pluripotent stem cells (iPSCs) from bats using a modified Yamanaka protocol. Their study also reveals that bat genomes harbor diverse and unusually abundant endogenous retroviruses (ERVs) that are reactivated during iPSC reprogramming.
Medical subject headings
- Chiroptera
- Induced Pluripotent Stem Cells
- Endogenous Retroviruses