Uncommon Manifestation of Oligometastatic Prostate Cancer: Sister Mary Joseph Nodule.

Luna, Cibele; Kryvenko, Oleksandr N; Martinez, Jose; Singal, Rakesh; Kuker, Russ · Clin Nucl Med · 2023

case_report · Level V

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Abstract

A 76-year-old man with a history of prostate cancer diagnosed in 2008 developed biochemical recurrence in 2010 and started intermittent androgen deprivation therapy. In 2021, due to rising prostate-specific antigen, an 18 F-piflufolastat PSMA PET/CT was performed. It showed a radiotracer-avid sclerotic lesion in the right iliac bone and an indeterminate radiotracer-avid nodule in the umbilical region, demonstrating progressive enlargement and increased uptake on subsequent imaging. Pathologic analysis of the umbilical nodule revealed metastatic prostate cancer-a finding eponymically referred to as a Sister Mary Joseph nodule.

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