PhaGAA: an integrated web server platform for phage genome annotation and analysis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36882183.
- Also identified by DOI 10.1093/bioinformatics/btad120 and PMC identifier 10013646.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Phage genome annotation plays a key role in the design of phage therapy. To date, there have been various genome annotation tools for phages, but most of these tools focus on mono-functional annotation and have complex operational processes. Accordingly, comprehensive and user-friendly platforms for phage genome annotation are needed. Here, we propose PhaGAA, an online integrated platform for phage genome annotation and analysis. By incorporating several annotation tools, PhaGAA is constructed to annotate the prophage genome at DNA and protein levels and provide the analytical results. Furthermore, PhaGAA could mine and annotate phage genomes from bacterial genome or metagenome. In summary, PhaGAA will be a useful resource for experimental biologists and help advance the phage synthetic biology in basic and application research. PhaGAA is freely available at http://phage.xialab.info/.
Medical subject headings
- Bacteriophages