Chronic Active Epstein-Barr Virus (EBV) Infection Controlled by Allogeneic Stem Cell Transplantation and EBV-Specific T Cells.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 36883586.
- Also identified by DOI 10.1093/cid/ciad131.
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Abstract
We report sustained remission of chronic active Epstein-Barr virus (EBV) infection in a 27-year-old female patient treated with third-party EBV-specific T cells followed by allogeneic hematopoietic stem cell transplantation (HSCT). The viremia cleared after administration of anti-T-lymphocyte globulin for graft-versus-host disease (GvHD) prophylaxis. Subsequent expansion of EBV-infected host T cells was controlled by transfusion of donor-derived EBV-specific T cells.
Medical subject headings
- Epstein-Barr Virus Infections
- Hematopoietic Stem Cell Transplantation
- Graft vs Host Disease