Unanticipated metabolic plasticity in response to chronic hypoxia.

Papandreou, Ioanna; Benej, Martin; Denko, Nicholas C · Cell Metab · 2023

other · Level V

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Abstract

In this issue of Cell Metabolism, Midha et al. investigate the metabolic changes in mice after exposure to reduced oxygen tension for an acute or chronic duration. Their organ-specific findings may help explain physiological observations in humans living at high altitude but raise additional questions concerning pathological hypoxia after vascular damage or in cancer.

Medical subject headings